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Journal Articles

Clinical characteristics of children receiving antipsychotic medication

Findling RL, Sarah (Sally) M. Horwitz, Birmaher B, Kowatch RA, Fristad MA, Youngstrom EA, Frazier TW, Axelson D, Ryan N, Demeter CA, Depew J, Fields B, Gill MK, Deyling EA, Rowles BM, Arnold LE
Journal of Child and Adolescent Psychopharmacology , 2011

This study explored the demographic and diagnostic features of children who were currently receiving antipsychotics compared to children who were receiving other psychotropics in a cohort of children with and without elevated symptoms of mania (ESM). Participants were recruited from 10 child outpatient mental health clinics associated with four universities. Guardians with children between 6-12 years who presented for new clinical evaluations completed the Parent General Behavior Inventory-10 Item Mania Scale (PGBI-10M).

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Journal Articles

Access to pediatric subspecialty care: a population study of pediatric rheumatology inpatients in California

Noelle Pineda, Chamberlain LJ, Jia Chan, Cidon MJ, Paul Wise
Arthritis Care & Research , 2011

OBJECTIVE:

To examine trends in the specialty care hospitalization of pediatric rheumatology patients and determine how nonclinical factors influence access.

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Journal Articles

Improving practice guidelines with patient-specific recommendations

Douglas Owens
Annals of Internal Medicine , 2011

Clinical practice guidelines aim to help providers make decisions that optimize patient care (1). Both developers and users of guidelines understand that guidelines could be improved by tailoring the recommendations to the specific circumstances of an individual patient. Tailored guideline recommendations may improve health outcomes when a group of patients can be divided into subgroups in which the tailored recommendations would increase benefits, reduce harms, or save costs relative to more generic recommendations.

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Journal Articles

Determinants of the cost of health services used by veterans with HIV

Barnett PG, Chow A, Vilija Joyce, Bayoumi AM, Griffin SC, Nosyk B, Mark Holodniy, Brown ST, Sculpher M, Anis AH, Douglas K. Owens
Medical Care , 2011

BACKGROUND:

The effect of adherence, treatment failure, and comorbidities on the cost of HIV care is not well understood.

OBJECTIVE:

To characterize the cost of HIV care including combination antiretroviral treatment (ART).

RESEARCH DESIGN:

Observational study of administrative data.

SUBJECTS:

Total 1896 randomly selected HIV-infected patients and 288 trial participants with multidrug-resistant HIV seen at the US Veterans Health Administration (VHA).

MEASURES:

Comorbidities, cost, pharmacy, and laboratory data.

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Journal Articles

The cost-effectiveness of symptom-based testing and routine screening for acute HIV infection in men who have sex with men in the USA

Juusola JL, Margaret Brandeau, Long EF, Douglas K. Owens, Eran Bendavid
AIDS , 2011

OBJECTIVE:

Acute HIV infection often causes influenza-like illness (ILI) and is associated with high infectivity. We estimated the effectiveness and cost-effectiveness of strategies to identify and treat acute HIV infection in men who have sex with men (MSM) in the USA.

DESIGN:

Dynamic model of HIV transmission and progression.

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Journal Articles

The potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: examining the RV144 trial results

Andersson KM, Paltiel AD, Douglas Owens
Vaccine , 2011

BACKGROUND:

The prime-boost HIV vaccine regimen used in the recent RV144 trial resulted in modest efficacy of 31% over 3.5 years, but was substantially higher in the first year post-vaccination. We sought to explore the potential impact of a vaccine with rapidly waning efficacy in a South African population.

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Journal Articles

A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction

Povsic TJ, O'Connor CM, Henry T, Taussig A, Kereiakes DJ, Fortuin FD, Niederman A, Schatz R, Spencer R 4th, Douglas K. Owens, Banks M, Joseph D, Roberts R, Alexander JH, Sherman W
American Heart Journal , 2011

BACKGROUND:

We sought to determine the safety and preliminary efficacy of transcatheter intramyocardial administration of myoblasts in patients with heart failure (HF).

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Journal Articles

Economic evaluation research in the context of Child Welfare policy: A structured literature review and recommendations.

Jeremy Goldhaber-Fiebert, Snowden LR, Wulczyn F, Landsverk J, Sarah (Sally) Horwitz
Child Abuse & Neglect , 2011

OBJECTIVES:

With over 1 million children served by the US Child Welfare system at a cost of $20 billion annually, this study examines the economic evaluation literature on interventions to improve outcomes for children at risk for and currently involved with the system, identifies areas where additional research is needed, and discusses the use of decision-analytic modeling to advance 

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Journal Articles

HIV-1 clade C envelopes obtained from late stage symptomatic Indian patients varied in their ability towards relative CD4 usages and sensitivity to CCR5 antagonist TAK-779

Gharu L, Ringe R, Jay Bhattacharya
Virus Research , 2011

The mechanism by which strictly CCR5 using HIV-1 clade C variants exacerbate disease progression in absence of coreceptor switch is not clearly known.

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Journal Articles

A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop

Ringe R, Sharma D, Zolla-Pazner S, Phogat S, Risbud A, Thakar M, Paranjape R, Jay Bhattacharya
Virology , 2011

Identification of vulnerability in the HIV-1 envelope (Env) will aid in Env-based vaccine design. We recently found an HIV-1 clade C Env clone (4-2.J45) amplified from a recently infected Indian patient showing exceptional neutralization sensitivity to autologous plasma in contrast to other autologous Envs obtained at the same time point.

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Journal Articles

Cost-effectiveness of an intensive telephone-based intervention for smoking cessation

Mark W. Smith, An LC, Fu SS, Nelson DB, Joseph AM
Journal of Telemedicine and Telecare , 2011

We calculated the incremental cost per quit of a telephone care intervention versus usual care using the provider's perspective. The study population was 819 smokers at five US Veterans Affairs (VA) primary care clinics. They enrolled in the clinical trial between June 2001 and December 2002. After 12 months the participants were assessed for short- and long-term abstinence over the previous six months. VA records were used to extract the cost of VA services over 12 months, and the cost of care purchased by the VA from others. Intervention costs were derived through micro-costing.

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Journal Articles

Quality-of-Care Indicators for Children With Sickle Cell Disease

C. Jason Wang, Patricia L. Kavanagh, Alison A. Little, Jaime Bruce Holliman, Philippa G. Sprinz
Pediatrics , 2011

OBJECTIVE: To develop a set of quality-of-care indicators for the management of children with sickle cell disease (SCD) who are cared for in a variety of settings by addressing the broad spectrum of complications relevant to their illness.

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Journal Articles

One-year outcomes of community-acquired and health care-associated pneumonia in the Veterans Affairs Health Care System

Hsu JL, Siroka AM, Mark W. Smith, Mark Holodniy, Meduri GU
International Journal of Infectious Disease , 2011

Abstract

BACKGROUND:

While studies have demonstrated higher medium-term mortality for community-acquired pneumonia (CAP), mortality and costs have not been characterized for healthcare-associated pneumonia (HCAP) over a 1-year period.

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Journal Articles

REM-related bradyarrhythmia syndrome

Jon-Erik Holty, Guilleminault C
Sleep Medicine Reviews , 2011
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Journal Articles

Opioids, Sleep, and Sleep-Disordered Breathing

Zutler M, Jon-Erik Holty
Current Pharmaceutical Design , 2011

Abstract

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Journal Articles

Surgically Induced Weight Loss Improve Daytime Sleepiness?

Jon-Erik Holty, Parimi N, Ballesteros M, Blackwell T, Cirangle PT, Jossart GH, Kimbrough ND, Rose JM, Stone K, Bravata DM
Obesity Surgery , 2011
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Books

BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats: Abbreviated Version

Douglas Owens
National Academies Press , 2011

Author information: IOM (Institute of Medicine) and NRC (National Research Council). (Committee: Goldstein BD, DeSimone JM, Ascher MS, Buehler JW, Cook KS, Crouch NA, Doyle FJ, Foldy S, Gursky EA, Hoffman S, Johnson CB, Keim P, Kellerman AL, Kleinman KP, Layton M, Lee EK, Mayor SD, Moshier TF, Murphy FA, Murray RW, Owens DK, Pollock SM, Resnick IG, Schaudies RP, Schultz JS)

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Journal Articles

Cost Effectiveness of Elective Induction of Labor at 41 Weeks in Nulliparous Women

Aaron B Caughey, Vandana Sundaram, Anjali J Kaimal, Yvonne W. Cheng, Allison Gienger, Sarah E Little, Jason Lee, Luchin Wong, Brian L Shaffer, Susan H Tran, Amy Padula, Kathryn M. McDonald, Elisa F Long, Douglas Owens, Dena Bravata
American Journal Of Obstetrics Gynecology , 2011

BACKGROUND: Induction of labor is on the rise in the U.S., increasing from 9.5 percent in 1990 to 22.1 percent in 2004. Although, it is not entirely clear what proportion of these inductions are elective (i.e. without a medical indication), the overall rate of induction of labor is rising faster than the rate of pregnancy complications that would lead to a medically indicated induction. However, the maternal and neonatal effects of induction of labor are unclear. Many studies compare women with induction of labor to those in spontaneous labor.

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Journal Articles

Multi-Country Analysis of Palm Oil Consumption and Cardiovascular Disease Mortality for Countries at Different Stages of Economic Development: 1980-1997

Brian K Chen, Ben Seligman, John W Farquar, Jeremy Goldhaber-Fiebert
Globalization and Health , 2011

Background

Cardiovascular diseases represent an increasing share of the global disease burden. There is concern that increased consumption of palm oil could exacerbate mortality from ischemic heart disease (IHD) and stroke, particularly in developing countries where it represents a major nutritional source of saturated fat.

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Books

Sourcebook Volume 1–Women Veterans in the Veterans Health Administration: Sociodemographic Characteristics and Use of VHA Care

Susan M. Frayne, Ciaran S. Phibbs, Sarah Friedman, Eric Berg, Lakshmi Ananth, Samina Iqbal, Patricia Hayes, Laura Herrera
Washington, DC : Women Veterans Health Stragetic Health Care Group, Dept. of Veterans Affairs, Veterans Health Administration , 2011

The Sourcebook is the result of ongoing Veterans Health Administration (VHA) efforts aimed at understanding the effects of military service on women’s lives.  The first in a series, Sourcebook Vol. 1 describes women Veterans receiving VHA care in Fiscal Year 2009 overall and within key subgroups (by age and by service-connected disability status). It also presents gender comparisons between women and men in FY09. Finally, it presents longitudinal trends in utilization over the decade (FY00–FY09).

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Journal Articles

Comparative Analysis of Old-Age Mortality Estimations in Africa

Eran Bendavid, Seligman, B, Kubo, J
PLoS ONE , 2011
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Journal Articles

Anaemia among students of rural China's elementary schools: Prevalence and correlates in Ningxia and Qinghai's poor counties

Luo, R., Zhang, L., Liu, C., Zhao, Q., Shi, Y., Grant Miller, Yu, E., Sharbono, B., Medina, A., Scott Rozelle, Martorell, R.
Journal of Health, Population and Nutrition , 2011
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