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    Journal Article

    Sanjay Basu, John S. Yudkin, Sylvia Kehlenbrink, Justine I. Davies, Sarah H. Wild, Kasia J. Lipska, Jeremy B. Sussman, David Beran
    The Lancet, 2018

    Background:

    The amount of insulin needed to effectively treat type 2 diabetes worldwide is unknown. It also remains unclear how alternative treatment algorithms would affect insulin use and disability-adjusted life-years (DALYs) averted by insulin use, given that current access to insulin (availability and affordability) in many areas is low. The aim of this study was to compare alternative projections for and consequences of insulin use worldwide under varying treatment algorithms and degrees of insulin access.

    Methods:

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    Journal Article

    Eric Sun, Thomas R. Miller, Jasmin Moshfegh, Laurence C. Baker
    The Journal of the American Society of Anesthesiologists , 2018

    The adjusted mortality for care teams with anesthesiologist assistants was 1.6% (95% CI, 1.4 to 1.8) versus 1.7% for care teams with nurse anesthetists (95% CI, 1.7 to 1.7; difference −0.08; 95% CI, −0.3 to 0.1; P = 0.47). Compared to care teams with nurse anesthetists, care teams with anesthesiologist assistants were associated with non–statistically significant decreases in length of stay (−0.009 days; 95% CI, −0.1 to 0.1; P = 0.89) and medical spending (−$56; 95% CI, −334 to 223; P = 0.70).

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    Journal Article

    Eran Bendavid, Eran Bendavid, Douglas K. Owens, Yushen Qian, Satoshi Muruyama
    2018

    The standard of care treatment for maximally resected, high risk (≥ 40 years old or sub-totally resected) low grade glioma (LGG) patients was established by RTOG 9802, which showed an overall survival (OS) of 13.3 years for patients treated with radiotherapy (RT) + PCV (procarbazine, lomustine [CCNU], vincristine) chemotherapy compared to 7.8 years for RT alone. In the era of value-based health care, cost-effectiveness analyses (CEA) have the potential to inform coverage decisions and patient care.

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    Journal Article

    Nagamani Kammili, Jyothi Lakshmi, Anlu Xing, Afia Khan, Manisha Rani, Prasanthi Kolli, Anlu Xing, Douglas K. Owens
    Emerging Infectious Diseases Journal, 2018

    The decreasing effectiveness of antimicrobial agents is a global public health threat, yet risk factors for community-acquired antimicrobial resistance (CA-AMR) in low-income settings have not been clearly elucidated. Our aim was to identify risk factors for CA-AMR with extended-spectrum β-lactamase (ESBL)–producing organisms among urban-dwelling women in India. We collected microbiological and survey data in an observational study of primigravidae women in a public hospital in Hyderabad, India.

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    Journal Article

    Maria Polyakova, M. Kate Bundorf, Daniel P. Kessler, Laurence C. Baker
    The American Journal of Managed Care , 2018

    In this study published in the American Journal of Managed Care, the authors found that premiums for ACA Marketplace plans were higher in rating areas in which physician, hospital, and insurance markets were less competitive.

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    Journal Article

    Eran Bendavid, Jennifer Burney, Marshall Burke
    Nature, 2018

    Poor air quality is thought to be an important mortality risk factor globally, but there is little direct evidence from the developing world on how mortality risk varies with changing exposure to ambient particulate matter. Current global estimates apply exposure-response relationships that have been derived mostly from wealthy, mid-latitude countries to spatial population data, and these estimates remain unvalidated across large portions of the globe.

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    Working Paper

    David C. Chan
    Stanford University, 2018

    Abstract: Learning on the job creates a tradeoff in team decisions: Workers with less knowledge have less to contribute to team decisions, but experiential learning may require that trainees also have a stake in decisions to learn. This paper studies learning and influence in team decisions among physicians trainees. Exploiting a discontinuity in relative experience, I find reduced-form evidence of influence due to seniority between trainees.

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    Working Paper

    David Chan, David C. Chan, Michael J. Dickstein
    Stanford University, 2018

    Abstract: In setting prices for physician services, Medicare solicits input from a committee that evaluates proposals from industry. We investigate whether this arrangement leads to prices biased toward the interests of committee members. We find that increasing a measure of affiliation between the committee and proposers by one standard deviation increases prices by 10%, demonstrating a pathway for regulatory capture. We then evaluate the effect of affiliation on the quality of information used in price-setting.

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    Journal Article

    Victor R. Fuchs
    JAMA, 2018

    The recent challenges to the Affordable Care Act (ACA), which has increased the number of individuals with health insurance in the United States but has had little effect on cost, has revived the debate about a single-payer health care system.

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    Journal Article

    Rebecca L. Haffejee, Michelle Mello
    The New England Journal of Medicine, 2017

    The opioid epidemic has claimed more than 300,000 lives in the United States since 20001

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    Working Paper

    Kim Babiarz, Jiwon Lee, Grant Miller, Tey Nai Peng, Christine Valente
    Center for Global Development, 2017

    There is longstanding debate about the contribution of family planning programs to fertility decline. Studying the staggered introduction of family planning across Malaysia during the 1960s and 1970s, we find modest responses in fertility behavior. Higher (but not lower) parity birth hazards declined by one-quarter—but imply only a 5 percent decline in the overall annual probability of birth. Age at marriage rose by 0.48 years, but birth spacing conditional on this did not otherwise change.

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    Journal Article

    Adam Isen, Maya Rossin-Slater, Reed Walker
    Proceedings of the National Academy of Sciences, 2017

    We study how exposure to extreme temperatures in early periods of child development is related to adult economic outcomes measured 30 y later. Our analysis uses administrative earnings records for over 12 million individuals born in the United States between 1969 and 1977, linked to fine-scale, daily weather data and location and date of birth.

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    Journal Article

    Maria Polyakova, Lynn M. Hua, M. Kate Bundorf
    Health Affairs, 2017

    The Affordable Care Act (ACA) has increased the number of Americans with health insurance. Yet many policy makers and consumers have questioned the value of Marketplace plan coverage because of the generally high levels of cost sharing. We simulated out-of-pocket spending for bronze, silver, or gold Marketplace plans (those having actuarial values of 60 percent, 70 percent, and 80 percent, respectively).

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    Journal Article

    Sanjay Basu, Jeremy B. Sussman, Seth A. Berkowitz, Rodney A. Hayward, Alain G. Bertoni, Adolfo Correa, Stanford Mwasongwe, John S. Yudkin
    American Diabetes Association, 2017
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    Journal Article

    Mark A. Hlatky, Dhruv S. Kazi
    Journal of the American College of Cardiology, 2017

    Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors substantially reduce low-density lipoprotein cholesterol, but it is presently unclear whether they also reduce mortality. The list prices of PCSK9 inhibitors in the United States (>$14,500 per year) are >100× higher than generic statins, and only a small fraction of their higher cost is likely to be recovered by prevention of cardiovascular events.

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    Journal Article

    Seth A. Berkowitz, Hilary K. Seligman, Joseph Rigdon, James B. Meigs, Sanjay Basu
    JAMA Internal Medicine, 2017

    Objective

    To determine whether the Supplemental Nutrition Assistance Program (SNAP), which addresses food insecurity, can reduce health care expenditures.

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    Journal Article

    Dario Tedesco, Davide Gori, Karishma Desai, Steven M. Asch, Ian R. Carroll, Catherine Curtin, Kathryn M. McDonald, Maria P. Fantini, Tina Hernandez-Boussard
    JAMA Surgery, 2017

    To systematically review and meta-analyze evidence of nonpharmacological interventions for postoperative pain management after total knee arthroplasty.

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    Journal Article

    Jonathan Shaw, Monica Farid, Claire Noel-Miller, Neesha Joseph, Ari Houser, Steven M. Asch, Jay Bhattacharya, Lynda Flowers
    SAGE Journals, 2017

    Objective: The purpose of this study was to evaluate the impact of objective isolation and loneliness on Medicare spending and outcomes. Method: We linked Health and Retirement Study data to Medicare claims to analyze objective isolation (scaled composite of

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    Working Paper

    Maya Rossin-Slater, Maya Rossin-Slater, Petra Persson
    American Economic Review, 2017

    This paper studies how in utero exposure to maternal stress from family ruptures affects later mental health. We find that prenatal exposure to the death of a maternal relative increases take-up of ADHD medications during childhood and anti-anxiety and depression medications in adulthood. Further, family ruptures during pregnancy depress birth outcomes and raise the risk of perinatal complications necessitating hospitalization. Our results suggest large welfare gains from preventing fetal stress from family ruptures and possibly from economically induced stressors such as unemployment.

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    Journal Article

    Sanjay Basu, Russell S. Phillips, Zirui Song, Asaf Bitton, Bruce E. Landon
    Health Affairs, 2017
    Capitated payments in the form of fixed monthly payments to cover all of the costs associated with delivering primary care could encourage primary care practices to transform the way they deliver care. Using a microsimulation model incorporating data from 969 US practices, we sought to understand whether shifting to team- and non-visit-based care is financially sustainable for practices under traditional fee-for-service, capitated payment, or a mix of the two.
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    Journal Article

    Marcella Alsan, Marianne Wanamaker
    The Quarterly Journal of Economics, 2017

    For forty years, the Tuskegee Study of Untreated Syphilis in the Negro Male passively monitored hundreds of adult black males with syphilis despite the availability of effective treatment.

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    Journal Article

    Anlu Xing, Paul H. Wise, Gary L. Darmstadt, Eran Bendavid
    Pediatrics, 2017

    Achieving gender equality in education is an important development goal.  We tested the hypothesis that the gender gap in adolescent education is accentuated by illnesses among young children in the household.

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