Health and Medicine

FSI’s researchers assess health and medicine through the lenses of economics, nutrition and politics. They’re studying and influencing public health policies of local and national governments and the roles that corporations and nongovernmental organizations play in providing health care around the world. Scholars look at how governance affects citizens’ health, how children’s health care access affects the aging process and how to improve children’s health in Guatemala and rural China. They want to know what it will take for people to cook more safely and breathe more easily in developing countries.

FSI professors investigate how lifestyles affect health. What good does gardening do for older Americans? What are the benefits of eating organic food or growing genetically modified rice in China? They study cost-effectiveness by examining programs like those aimed at preventing the spread of tuberculosis in Russian prisons. Policies that impact obesity and undernutrition are examined; as are the public health implications of limiting salt in processed foods and the role of smoking among men who work in Chinese factories. FSI health research looks at sweeping domestic policies like the Affordable Care Act and the role of foreign aid in affecting the price of HIV drugs in Africa.

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Importance  In rural India, as in many developing countries, childhood mortality remains high and the quality of health care available is low. Improving care in such settings, where most health care practitioners do not have formal training, requires an assessment of the practitioners’ knowledge of appropriate care and the actual care delivered (the know-do gap).

Objective  To assess the knowledge of local health care practitioners and the quality of care provided by them for childhood diarrhea and pneumonia in rural Bihar, India.

Design, Setting, and Participants  We conducted an observational, cross-sectional study of the knowledge and practice of 340 health care practitioners concerning the diagnosis and treatment of childhood diarrhea and pneumonia in Bihar, India, from June 29 through September 8, 2012. We used data from vignette interviews and unannounced standardized patients (SPs).

Main Outcomes and Measures  For SPs and vignettes, practitioner performance was measured using the numbers of key diagnostic questions asked and examinations conducted. The know-do gap was calculated by comparing fractions of practitioners asking key diagnostic questions on each method. Multivariable regressions examined the relation among diagnostic performance, prescription of potentially harmful treatments, and the practitioners’ characteristics. We also examined correct treatment recommended by practitioners with both methods.

Results  Practitioners asked a mean of 2.9 diagnostic questions and suggested a mean of 0.3 examinations in the diarrhea vignette; mean numbers were 1.4 and 0.8, respectively, for the pneumonia vignette. Although oral rehydration salts, the correct treatment for diarrhea, are commonly available, only 3.5% of practitioners offered them in the diarrhea vignette. With SPs, no practitioner offered the correct treatment for diarrhea, and 13.0% of practitioners offered the correct treatment for pneumonia. Diarrhea treatment has a large know-do gap; practitioners asked diagnostic questions more frequently in vignettes than for SPs. Although only 20.9% of practitioners prescribed treatments that were potentially harmful in the diarrhea vignettes, 71.9% offered them to SPs (P < .001). Unqualified practitioners were more likely to prescribe potentially harmful treatments for diarrhea (adjusted odds ratio, 5.11 [95% CI, 1.24-21.13]). Higher knowledge scores were associated with better performance for treating diarrhea but not pneumonia.

Conclusions and Relevance  Practitioners performed poorly with vignettes and SPs, with large know-do gaps, especially for childhood diarrhea. Efforts to improve health care for major causes of childhood mortality should emphasize strategies that encourage pediatric health care practitioners to diagnose and manage these conditions correctly through better monitoring and incentives in addition to practitioner training initiatives.

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Publication Type
Journal Articles
Publication Date
Journal Publisher
JAMA Pediatrics
Authors
Jeremy Goldhaber-Fiebert
Number
4

Stanford Health Policy
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Communications Manager
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Beth Duff-Brown became the Communications Manager at Stanford Health Policy in May 2015. She was the editorial director at the Center for International Security and Cooperation for three years before joining the health policy and research centers at the Freeman Spogli Institute for International Studies and the School of Medicine. Before coming to Stanford, Beth worked in Africa and Asia as a foreign correspondent for The Associated Press, including as bureau chief for South Asia, based in New Delhi, and as the Deputy Asia Editor at the Asia-Pacific Desk in Bangkok, overseeing the daily news report from Afghanistan to Australia. She was a 2010-2011 Knight Journalism Fellow at Stanford, where she developed a digital platform to tell stories about women and girls in the developing world. Beth has a master's degree in journalism from Northwestern University and was a Peace Corps Volunteer in the Democratic Republic of the Congo.

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Objective. To quantify the differential impact on hospital performance of three readmission metrics: all-cause readmission (ACR), 3M Potential Preventable Readmission (PPR), and Centers for Medicare and Medicaid 30-day readmission (CMS).

Data Sources. 2000–2009 California Office of Statewide Health Planning and Development Patient Discharge Data Nonpublic file.

Study Design. We calculated 30-day readmission rates using three metrics, for three disease groups: heart failure (HF), acute myocardial infarction (AMI), and pneumonia. Using each metric, we calculated the absolute change and correlation between performance; the percent of hospitals remaining in extreme deciles and level of agreement; and differences in longitudinal performance.

Principal Findings. Average hospital rates for HF patients and the CMS metric were generally higher than for other conditions and metrics. Correlations between the ACR and CMS metrics were highest (r = 0.67–0.84). Rates calculated using the PPR and either ACR or CMS metrics were moderately correlated (r = 0.50–0.67). Between 47 and 75 percent of hospitals in an extreme decile according to one metric remained when using a different metric. Correlations among metrics were modest when measuring hospital longitudinal change.

Conclusions. Different approaches to computing readmissions can produce different hospital rankings and impact pay-for-performance. Careful consideration should be placed on readmission metric choice for these applications.

 

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Publication Type
Journal Articles
Publication Date
Journal Publisher
Health Services Research
Authors
Olga Saynina
Laurence C. Baker
Number
6, Part 1
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OBJECTIVE
To quantify the limitations associated with restricting readmission metrics to same-hospital only readmission.
DESIGN
Using 2000-2009 California Office of Statewide Health Planning and Development Patient Discharge Data Nonpublic file, we identified the proportion of 7-, 15- and 30-day readmissions occurring to the same hospital as the initial admission using All-cause Readmission (ACR) and 3M Corporation Potentially Preventable Readmissions (PPR) Metric. We examined the correlation between performance using same and different hospital readmission, the percent of hospitals remaining in the extreme deciles when utilizing different metrics, agreement in identifying outliers and differences in longitudinal performance. Using logistic regression, we examined the factors associated with admission to the same hospital.
RESULTS
68% of 30-day ACR and 70% of 30-day PPR occurred to the same hospital. Abdominopelvic procedures had higher proportions of same-hospital readmissions (87.4-88.9%), cardiac surgery had lower (72.5-74.9%) and medical DRGs were lower than surgical DRGs (67.1 vs. 71.1%). Correlation and agreement in identifying high- and low-performing hospitals was weak to moderate, except for 7-day metrics where agreement was stronger (r = 0.23-0.80, Kappa = 0.38-0.76). Agreement for within-hospital significant (P < 0.05) longitudinal change was weak (Kappa = 0.05-0.11). Beyond all patient refined-diagnostic related groups, payer was the most predictive factor with Medicare and MediCal patients having a higher likelihood of same-hospital readmission (OR 1.62, 1.73).
CONCLUSIONS
Same-hospital readmission metrics are limited for all tested applications. Caution should be used when conducting research, quality improvement or comparative applications that do not account for readmissions to other hospitals.

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Publication Type
Journal Articles
Publication Date
Journal Publisher
International Journal for Quality in Health Care
Authors
Olga Saynina
Laurence C. Baker
Number
6
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Abstract:  The Agency for Healthcare Research and Quality Patient Safety Indicators (PSIs) do not capture complications arising after discharge. This study sought to quantify the bias related to omission of readmissions for PSI-qualifying conditions. Using 2000-2009 California Office of Statewide Health Planning and Development Patient Discharge Data, the study team examined the change in PSI rates when including readmissions in the numerator, hospitals performing in the extreme deciles, and longitudinal performance. Including 7-day readmissions resulted in a 0.3% to 8.9% increase in average hospital PSI rates. Hospital PSI rates with and without PSI-qualifying 30-day readmissions were highly correlated for point estimates and within-hospital longitudinal change. Most hospitals remained in the same relative performance decile. Longer length of stay, public payer, and discharge to skilled nursing facilities were associated with a higher risk of readmission for a PSI-qualifying event. Failure to include readmissions in calculating PSIs is unlikely to lead to erroneous conclusions.

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Publication Type
Journal Articles
Publication Date
Journal Publisher
American Journal of Medical Quality
Authors
Olga Saynina
Laurence C. Baker
Number
2
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Please note: All research in progress seminars are off-the-record. Any information about methodology and/or results are embargoed until publication.

Abstract:

Conventional wisdom suggests that if private health insurance plans compete alongside a public option, they may endanger the latter's financial stability by cream-skimming good risks. Documenting cream-skimming in dual insurance systems is challenging because of the co-existence of selection and moral hazard. I use a fuzzy regression discontinuity design based on exogenous variation in the propensity of choosing private health insurance to address this challenge. The empirical setting is Germany, where there exists an unsubsidized non-group for-profit private health insurance market in parallel to a statutory alternative. Federal regulation mandates individuals with income below an annually set threshold to enroll into the statutory system. I do not find compelling support for concerns of cream-skimming by private insurers. Using a discrete choice model of demand for private insurance, I explore heterogeneous preferences and long-term contract design of private insurers as potential explanations for this optimistic result about insurance design.

Maria Polyakova Assistant Professor Health Research and Policy
Seminars
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Please note: All research in progress seminars are off-the-record. Any information about methodology and/or results are embargoed until publication.

Abstract:

Ulcerative colitis is typically treated with medications including steroids and immunomodulators; patients refractory to medications undergo curative surgical resection of the colon and rectum. In 2005, biologic therapy was approved for ulcerative colitis as it improves short-term remission rates, but the long-term clinical benefit is unknown. The aims of the study are to assess the effect of biologics on the need for surgery in ulcerative colitis, describe treatment patterns for ulcerative colitis, and measure the economic impact of biologic therapy in the management of the disease.  Results demonstrate an increase in the use of biologics for ulcerative colitis, no change in rates of surgery for ulcerative colitis after approval of biologics, and dramatically increased overall costs.

Cindy Kin
Seminars
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Prescription opioids provide much needed relief to people in acute pain, but are also widely misused, leading to addiction and over one thousand overdose deaths per month. As the annual number of prescriptions has soared to over 200 million, policymakers have been struggling with how to limit the risks of these medications while at the same time keeping them available for people in pain. In this Stanford Health Policy Forum, addiction medicine expert Anna Lembke, M.D. and pain medicine expert Sean Mackey, M.D., Ph.D., will debate and discuss how to balance the benefits and costs of prescription opioids.

Guest Speakers:

Dr. Anna Lembke received her undergraduate degree in Humanities from Yale University and her medical degree from Stanford University. She is on the faculty of the Stanford University School of Medicine, a diplomate of the American Board of Psychiatry and Neurology, and a diplomate of the American Board of Addiction Medicine. She is the Program Director for the Stanford Addiction Medicine Program and Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic.

Under Dr. Sean Mackey’s leadership, researchers at the Stanford Pain Management Center and the Stanford Systems Neuroscience and Pain Laboratory (SNAPL) have made major advances in the understanding of chronic pain as a disease in its own right, one that fundamentally alters the nervous system. Dr. Mackey has overseen efforts to map the specific brain and spinal cord regions that perceive and process pain, which has lead to the development of a multidisciplinary treatment model that translates basic science research into innovative therapies to provide more effective, personalized treatments for patients with chronic pain.

Moderator:

Paul Costello is Chief Communications Officer at the Stanford School of Medicine.

For event details, visit http://med.stanford.edu/healthpolicyforum/event-calendar.html.

Berg Hall
291 Campus Dr.
Stanford, CA 94305

Panel Discussions
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All research in progress seminars are off-the-record. Any information about methodology and/or results are embargoed until publication

Abstract:

Studying physicians in training, I investigate how uncertainty and tacit knowledge may give rise to significant practice variation, via learning and influence in organizations. Consistent with tacit learning, and empirically exploiting a discontinuity in the formation of teams, I find that relative experience substantially increases the influence of a physician on variation. Learning sufficient to generate convergence exists in specialist-driven services but not in the generalist-driven service, a difference unexplained by formal diagnostic codes. Convergence in specialist services occurs with both general and specific experience. In contrast to learning and influence, rich physician characteristics correlated with preferences and ability determine little if any variation.

CHP/PCOR
Seminars
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Please note: All research in progress seminars are off-the-record. Any information about methodology and/or results are embargoed until publication

Abstract:

This talk will introduce new quantitative data on over 1000 social, economic, and environmental policies in 193 countries.  It will open a discussion on how the global data revolution could transform how we can examine what works to address social inequalities and their impact on global health.

Please join us after the seminar for light refreshments with the presenter.

Jody Heymann Dean UCLA Fielding School of Public Health
Seminars
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