Addressing the Harms of Market-Driven Drug Development

Addressing the Harms of Market-Driven Drug Development

Stanford researchers address a persistent flaw in the U.S. health system: prioritizing treatment investment based on market potential rather than medical necessity.
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The diseases causing the most suffering and death in the United States do not always attract investment in new treatments. That’s the disconnect exposed in a new report from the National Academies of Sciences, Engineering, and Medicine, co-authored by Stanford Law School Professor Lisa Larrimore Ouellette, a leading voice on intellectual property and medical innovation policy.  Stanford Health Policy Professor Joshua Salomon, a senior fellow at the Freeman Spogli Institute for International Studies, also served on the 16-member committee that drafted the report.

Aligning Investments in Therapeutic Development with Therapeutic Need: Closing the Gap calls out a persistent flaw in the U.S. health innovation system: Drug development is often driven more by market potential than by medical necessity. The result? Lifesaving treatments remain elusive for conditions like heart disease and mental illness – even as resources pour into more commercially promising areas such as oncology. According to the report, this misalignment not only distorts innovation but deepens health disparities and costs lives.

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